Page 1 Page 2 Page 3 Page 4 Page 5 Page 6 Page 7 Page 8STRIVING FOR A CURE A gift to the Campaign has enabled Matthew Holmes to study for his PhD with a team investigating the use of viruses to fight back against cancer. Working in the Leeds Institute of Molecular Medicine, Matthew is testing viruses for the treatment of Non-Hodgkin Lymphoma, a cancer of the lymph nodes with a very poor prognosis to patients. Oncolytic (cancer killing) viruses potentially work two ways – killing cancer cells and kick-starting the body’s immune system to fight against the tumour. A trial using a virus to treat skin cancer has already reported positive results, and the Leeds researchers believe similar treatments have the potential to be used in cancers of the brain, liver, bladder, colon, lung and prostate. Says Matthew: “Manipulating a virus to infect and kill cancer cells has fascinated me since I was first introduced to the concept during my degree studies. This scholarship has given me the opportunity to work as part of an internationally renowned team – and the preliminary data has been very promising. “I intend to take full advantage of all opportunities that are afforded to me during this scholarship so that I can advance my research experience and contribute towards advancing our understanding of how viruses might offer a new treatment for this devastating disease.” 4 PhD Scholarships